Endocrine Abstracts

Background: People with type 2 Diabetes Mellitus (DM2) more predisposed to Non-Alcoholic Fatty Liver Disease (NAFLD). Accompanied chronic pancreatitis impaired glycemic control by affecting gastrointestinal absorption, also by affecting of pancreatic insulin secretion. We study the frequency of NAFLD in DM2 patients with accompanied chronic pancreatitis.Material and Methods: In 44 people with DM2 blood glucose, HbA1c, Cholesterol, triglycerides, LDLP, HD...

Introduction: Metabolic syndrome (MetS) is combined groups of diseases with common pathogenesis and clinical signs and symptoms. Usually MS starts with obesity and last step appeared as a Diabetes Mellitus. We aimed to compare clinical signs and patients complaints according to type of manifestation of MetS.Material and Methods: Patients data, clinical complaints, anthropometric, biochemical parameters in 248 patients with various manifestations of the M...

There are three main types of diabetes mellitus: type 1 diabetes mellitus (T1DM), type 2 diabetes mellitus (T2DM) and gestational diabetes, with the first two types making about 99% of cases.According to its nature, type 1 diabetes mellitus (T1DM) is considered as a typical autoimmune disorder characterized with specific autoantibodies. Immunological markers of the diabetes mellitus onset can be found not only in T1DM with its specific clinical picture, ...

The fat tissue inflammation and insulin resistance formation are common in obesity and type 2 diabetes mellitus. The tumor necrosis factor–α (TNF-α), a pro-inflammatory cytokine, was found to be a key one in onset and progression of insulin resistance, blocking the insulin signaling pathway and hampering the gene expression of GLUT4, the intracellular insulin-regulated glucose transporter in body tissues. Rise in the TNF-α concentration in blood serum is b...

Obesity of varying severities can be seen in the vast majority of patients with type 2 diabetes mellitus (DM2). Oxidative stress is considered as a key pathogenetic link in the formation of metabolic disorders in obesity. The work was initiated to assess intensity of oxidative stress in obese patients with DM2.Materials and methodsThe patients were divided into 3 groups. Patients with DM2 and BMI > 30 kg/m2 were incl...

Background and Aims: Arterial stiffness is associated with increased risk for target organ damage, cardiovascular events and overall mortality in the general population, patients with diabetes mellitus (DM) and patients with chronic kidney disease (CKD) of all stages. The aim of this study is assessment of pulse wave velocity (PWV) in patients with type 2 diabetes at different stages of diabetic nephropathy and without it.Materials and Methods: We examin...